Multiple user configuration for Spamassassin

i am working on mailbox server and want to apply spamassassin for it. In spam assassin i want to use whitelisting and blacklisting features based on user, for example i have two user user1 and user2 while recieving the message from i want that this particular email addr ( should be whitlisted for user1 while on other side i want that same email addr ( should be blacklisted for user2. if i will whitlist or balclist particlar addr( in than it will be a site wide whitelist/blacklist i.e. it will be applicable for all user. it will be better if someone suggest a scipt/file which will be render for list of whitlist/blacklist on based of user.