I normally use Macromedia DreamWeaver (mostly in code view) for my sites, but I occasionally use Windows Wordpad too.
If you are not familiar with HTML, CSS etc. I would suggest searching Google for some tutorials and learning at least the basics before beginning.
Another option would be to use some form of content management system, such as WordPress or Joomla, which are both available as 'one-click installs' via the panel. You will find them in the Goodies -> One-Click Installs section.
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