It’s a little hard to know what your main emphasis is from your question. as "trouble tickets, knowledgebase, CRM"
are, to my way of thinking, very different kinds of software fauna.
I have installed, and played with, several such products on Dreamhost over the years (owl, knowledge Tree, Sugar CRM, assorted php groupware products, etc.), and find that, generally speaking, the Dreamhost featureset is more than adequate for these types of programs.
What is the principal purpose of the software you are looking to implement (trouble ticket management? knowledgebase/wiki? or CRM)?
There is no shortage of these on the “FLOSS” (Free/Libre Open Source Software) world, and many of them run well at/on Dreamhost, with the notable exceptioon of products that are “java/tomcat” JSP type pages, which DH does not support. Some can be demo’d at OpenSourceCMS.com, and others are easily enough located on sourceforge.net. There are even such software packages that run as components under Joomla (which is available at Dreamhost as a “one-click” install, as is “ActiveCollab”).
I’m just not familiar enough with “SupportWizard” to know exactly what you are looking for here.