HELP! "Error establishing a database connection"

HELP!!! My webmaster is out of town and this message comes up when you go to my site!! HELP!!! Any idea what this means/?

well apparently whatever script your site is using is unable to access the mysql database (im assuming its mysql). how long has this been happening? have you checked the dh status blog to see if there is an issue impacting your account? was anything changed recently? what is your website so we can look at it?